Trazodone for Dogs: Uses, Dose & Side Effects
Veterinary references checked with PetHealth+ · Last reviewed June 2026
By Kaiser Khan , Founder Veterinary references checked with PetHealth+ ( process ) Last reviewed Cite this page How we research & review
Trazodone is a prescription medication vets use for anxiety, fireworks fear, and post-surgery rest. Only use the dose your vet prescribes — sedation and low blood pressure are possible side effects.
Common uses
Noise phobias, vet visits, travel, and confinement after orthopaedic surgery.
Side effects
Sedation, ataxia, and gastrointestinal upset.
Never combine
Without vet approval — interactions with other sedatives are risky.
Related: Separation anxiety · Fireworks and pets
Frequently asked questions
How fast does trazodone work?
Often within 1–2 hours for situational anxiety.
Can trazodone be used daily?
Some dogs take it long-term under veterinary monitoring.
Is trazodone the same as acepromazine?
No — different drug classes with different effects.
What if my dog vomits after trazodone?
Give with food next time and tell your vet if vomiting persists.